rac Ambrisentan-d3 Methyl Ester - Names and Identifiers
rac Ambrisentan-d3 Methyl Ester - Physico-chemical Properties
Molecular Formula | C23H24N2O4
|
Molar Mass | 392.44766 |
Melting Point | 123-125°C |
Solubility | DMSO (Sparingly), Methanol (Sparingly), |
Appearance | Solid |
Color | Off-White to Pale Yellow |
Storage Condition | Refrigerator |
rac Ambrisentan-d3 Methyl Ester - Introduction
rac Ambrisentan-d3 Methyl Ester (rac abrisetan-d3 Methyl Ester) is a commonly used labeled compound in drug research. It is Ambrisentan-d3 (abrisetan-d3) the Methyl Ester derivatives. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Molecular formula: C24H26D3N3O3
-Molecular weight: 396.55g/mol
-Appearance: Colorless or white crystalline solid
-Melting point: 109-111 ° C
-Solubility: Soluble in organic solvents such as chloroform, methanol and dimethyl sulfoxide
Use:
- rac Ambrisentan-d3 Methyl Ester is mainly used for pharmacokinetic studies, bioavailability evaluation and internal standard substances in drug analysis.
-It can be used as an agonist of known structure, as a control or as a fluorescently labeled compound to track drug metabolism, drug transport and drug interactions in research.
Preparation Method:
- rac Ambrisentan-d3 Methyl Ester can be obtained by reacting Ambrisentan-d3 with formic acid, hydrogen formate or Methyl formate, and then purifying it.
-The preparation process needs to be carried out under an inert atmosphere and operated according to the specific synthesis steps and reaction conditions.
Safety Information:
- rac Ambrisentan-d3 Methyl Ester is a laboratory chemical and should be used in accordance with the standard operating procedures and safe operating guidelines for chemical experiments.
-Wear protective glasses and gloves when using, and ensure that the workplace has good ventilation.
-Avoid contact with skin and inhalation of dust during handling and storage.
-Keep away from light in a dry, ventilated place, and away from fire and oxidizing agents.
-Toxicity and safety data on this compound can be obtained in the relevant literature or in the Material Safety Data Sheet (MSDS) for detailed information.
Please note that for the use and operation of any chemical substances, appropriate safe operating procedures should be followed, and relevant regulations and regulations in the laboratory or industrial environment should be followed.
Last Update:2024-04-09 15:18:06